Biospective specializes in advanced image processing and statistical image analysis for human brain imaging studies, including Phase I-III clinical trials. We are fully GCP and 21 CFR Part 11 compliant. We have a solid track-record of delivering data of the highest quality to our sponsors.

Our fully-automated PIANO™ software is the only comprehensive package available for multi-modality MRI and PET studies.

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1.5 and 3T MRI

  • Anatomical imaging
  • Cerebral cortical thickness and volume
  • Hippocampal volume
  • Ventricular volume
  • Subcortical volumes
  • Volume-based morphometry (VBM)
  • Tensor-based morphometry (TBM)
  • Diffusion imaging
  • Magnetization transfer (MT) imaging
  • Arterial spin labeling (ASL) perfusion imaging
  • Resting-state and task-based BOLD fMRI
  • MR spectroscopy (MRS)

Human imaging mri

Brain PET

  • Amyloid imaging
  • Receptor mapping


Our Expertise

  • Neurodegenerative Diseases

  • Alzheimer’s Disease
  • Parkinson’s Disease
  • Multiple Sclerosis
  • Psychiatric Diseases

  • Schizophrenia
  • Tourette Syndrome
  • Pediatric Studies

  • Autism
  • ADHD
  • Lysosomal Storage Diseases

Do not hesitate to contact us to discuss studies for other CNS diseases.

Posters & Publications

Charil A, Carbonell F, Zijdenbos AP, Evans AC, Koeppe RA, Sevigny J, Chiao P, Bedell BJ. Comparison of reference regions for [18F]Florbetapir PET SUVR computation. Human Amyloid Imaging Conference 2014, Miami, FL, USA.
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Carbonell F, Charil A, Zijdenbos AP, Evans AC, Sevigny J, Chiao P, Bedell BJ. Statistically-driven automated subject classification based on amyloid PET scans. Human Amyloid Imaging Conference 2014, Miami, FL, USA.
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Lerch JP, Pruessner JC, Zijdenbos A, Hampel H, Teipel SJ, Evans AC. Focal decline of cortical thickness in Alzheimer disease identified by computational neuroanatomy. Cereb Cortex 2005;15(7):995-1001.
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Our experts are always available to meet your specific needs. Please do not hesitate to contact our clinical team.

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